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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Targeting triple‐negative breast cancer with an aptamer‐functionalized nanoformulation: a synergistic treatment that combines photodynamic and bioreductive therapies

Fig. 4

The cytotoxic effect of nanoVector, TPZ@LXL-1-PpIX-MMT-2, under hypoxia condition. a Cell viabilities of MDA-MB-231 treated with 0.4 µM of PpIX, 60 µM of TPZ, PpIX + TPZ, and TPZ@LXL-1-PpIX-MMT-2 under various oxygen levels (5 %, 2 %, 1 %). Photoirradiation was performed 5 h after treatment, and the irradiation time was 1 min. No treatment was received by control group. b Coefficient of Drug Interaction (CDI) of various chemotherapeutic treatments for TNBC cells. MTT assay was conducted to determine the viability 24 h after treatment. All experiments were performed at least in triplicate; all data are expressed as the mean ± standard deviation

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Journal of Nanobiotechnology

ISSN: 1477-3155

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