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Table 1 Mean and standard deviation of the percentage of drug encapsulation efficiency (DEE), drug loading (DL), nanoparticle recovery, nanoparticle size (z-average diameter), zeta potential (ζ) and polydispersity index of MSN-PLGA/Blank, CHX-loaded/MSN and CHX-loaded/MSN-PLGA at 25 and 50 mg of CHX incorporation, respectively

From: pH-dependent delivery of chlorhexidine from PGA grafted mesoporous silica nanoparticles at resin-dentin interface

Groups DEE (%) DL (%) Nanoparticle recovery (%) z-Average diameter (nm) Zeta potential (mV) Polydispersity index
MSN-PLGA/Blank 57.1 ± 11.6A 107.4 ± 7.4A − 15.4 ± 1.9A 0.27 ± 0.02A
25:50 CHX/MSN 81.4 ± 5.9A 15.3 ± 2.3A 65.5 ± 13.9B 97.9 ± 4.1B 23.6 ± 9.9B 0.18 ± 0.04B
50:50 CHX/MSN 85.4 ± 3.7A 19.7 ± 1.9AB 66.8 ± 12.8B 84.2 ± 5.9C 29.5 ± 9.4B 0.15 ± 0.01B
25:50:50 CHX/MSN-PLGA 92.7 ± 6.6B 20.4 ± 2.5B 67.6 ± 11.4B 81.2 ± 3.4C 41.3 ± 8.1C 0.083 ± 0.01C
50:50:50 CHX/MSN-PLGA 95.8 ± 5.6C 24.1 ± 3.1B 64.1 ± 15.2B 74.9 ± 4.6D 42.9 ± 6.7C 0.065 ± 0.01D
  1. Dissimilar uppercase letters show statistical significance at p < 0.05 within each column