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Table 1 Mean and standard deviation of the percentage of drug encapsulation efficiency (DEE), drug loading (DL), nanoparticle recovery, nanoparticle size (z-average diameter), zeta potential (ζ) and polydispersity index of MSN-PLGA/Blank, CHX-loaded/MSN and CHX-loaded/MSN-PLGA at 25 and 50 mg of CHX incorporation, respectively

From: pH-dependent delivery of chlorhexidine from PGA grafted mesoporous silica nanoparticles at resin-dentin interface

Groups

DEE (%)

DL (%)

Nanoparticle recovery (%)

z-Average diameter (nm)

Zeta potential (mV)

Polydispersity index

MSN-PLGA/Blank

–

–

57.1 ± 11.6A

107.4 ± 7.4A

− 15.4 ± 1.9A

0.27 ± 0.02A

25:50 CHX/MSN

81.4 ± 5.9A

15.3 ± 2.3A

65.5 ± 13.9B

97.9 ± 4.1B

23.6 ± 9.9B

0.18 ± 0.04B

50:50 CHX/MSN

85.4 ± 3.7A

19.7 ± 1.9AB

66.8 ± 12.8B

84.2 ± 5.9C

29.5 ± 9.4B

0.15 ± 0.01B

25:50:50 CHX/MSN-PLGA

92.7 ± 6.6B

20.4 ± 2.5B

67.6 ± 11.4B

81.2 ± 3.4C

41.3 ± 8.1C

0.083 ± 0.01C

50:50:50 CHX/MSN-PLGA

95.8 ± 5.6C

24.1 ± 3.1B

64.1 ± 15.2B

74.9 ± 4.6D

42.9 ± 6.7C

0.065 ± 0.01D

  1. Dissimilar uppercase letters show statistical significance at p < 0.05 within each column