Fig. 8From: Administration route governs the therapeutic efficacy, biodistribution and macrophage targeting of anti-inflammatory nanoparticles in the lungThe i.t. administration of P12 targeting pulmonary macrophages. a Gating strategy of flow cytometry analysis to identify macrophages (MΦ), monocytes (Mo), dendritic cells (DC) and neutrophils (PMN) in the BALF and single cell suspensions of lung tissues. b Flow histogram of P12-Cy5 in the MΦ, Mo, DC and PMN from the BALF; P12 was administered by the three different routes. c The mean fluorescence intensity (MFI) of P12-Cy5 in the MΦ, Mo, DC and PMN from the BALF (left) and lung tissue (right); P12 was treated intratracheally. ****p < 0.0001 vs. all the other groupsBack to article page