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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Development of a chitosan‐modified PLGA nanoparticle vaccine for protection against Escherichia coli K1 caused meningitis in mice

Fig. 4

The freeze-dried VoNPs were stable for at least 180 days. a Changes of particle size, PDI and zeta potential (from left to right) of the VoNPs after storage at 4 °C for 30, 90 and 180 days. n.s. no significant difference; *P < 0.05. b MALDI-TOF mass spectrometry of blank nanoparticles (BNPs), Vo protein, and the VoNPs after storage at 4 °C for 180 days. The arrow indicates the Vo protein with an m/z of approximately 15,245

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