Fig. 6From: Development of a chitosan‐modified PLGA nanoparticle vaccine for protection against Escherichia coli K1 caused meningitis in micea In vitro protein release of Vo from VoNPs. The bars represent the means ± standard error of the release ratio for three samples. b Nude mice were intramuscularly administrated green fluorescent protein (GFP) or GFP encapsulated in nanoparticles (GFP-NP). The mice were sequentially imaged from 0.5 to 48 h using an IVIS spectrum imaging system. c Quantitation of fluorescence intensity from the IVIS system. The data are presented as the means ± standard error (n = 3). *P < 0.05Back to article page