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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC

Fig. 6

a In vivo evaluation of the T2 weighted images of nude mice bearing orthotopic HCC tumor at before and after administration of MPDA@SPIO/SA-PEI/AFP-Fth, MPDA@SPIO/PEI/AFP-Fth, SA-PEI/AFP-Fth for 6, 12, 24, 48 h respectively, and untreated mice were scanned as control group. The red dash cycle indicated the tumor site. b MRI SNR of tumor site in different groups at pre-injection and 6, 12, 24, 48 h of post-injection. c The expression of ferritin in MPDA@SPIO/SA-PEI/AFP-Fth, MPDA@SPIO/PEI/AFP-Fth, SA-PEI/AFP-Fth and control group. (n = 3; *p < 0.05; **p < 0.01)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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