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Table 1 Physicochemical characterization of the formulated nanoparticles

From: Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC

Sample

Mass ratio

Size (nm)

Polydispersity Index (PI)

Zeta potential (mv)

MPDA@SPIO

 

135.04 ± 6.4

0.229 ± 0.292

− 17.27 ± 0.9

SA-PEI/AFP-Fth

0/1.25/1

105.04 ± 0.8

0.188 ± 0.058

28.4 ± 0.4

MPDA@SPIO/SA-PEI/AFP-Fth

5/1.25/1

144.98 ± 5.6

0.090 ± 0.043

20.40 ± 0.8

MPDA@SPIO/SA-PEI/AFP-Fth

10/1.25/1

148.66 ± 10.4

0.189 ± 0.027

15.10 ± 1.4

MPDA@SPIO/SA-PEI/AFP-Fth

20/1.25/1

168.17 ± 8.3

0.245 ± 0.007

10.87 ± 0.5