Fig. 8
From: A non-invasive nanoparticles for multimodal imaging of ischemic myocardium in rats
MR imaging in vitro and in vivo. T2-WI (a) and signal intensity (b) of IMTP-Fe3O4-PFH NPs at different Fe concentrations in vitro. c The curve of 1/T2 versus Fe concentration under T2-weighted MR scanning. The slope indicated the specific relativity r2. d T2*WI of the hearts after intravenous injection of IMTP-Fe3O4-PFH NPs, Fe3O4-PFH NPs, and IMTP -PFH NPs respectively. The top row showed grayscale images, and the bottom row showed the pseudo-coloring images. Red arrows pointed to the ischemic myocardium area. e Prussian blue & DAB staining of the ischemic myocardium area in different groups after MR imaging (scale bar = 50 μm). Black arrows pointed to brown stained iron. f Quantitative analysis of enhanced cardiac MR signal intensity between each group in vivo