Fig. 1
Preparation and characterization of PMAA-Fe and Cyp-PMAA-Fe@MSCs. a TEM image of PMAA-Fe. b TEM image of Cyp-PMAA-Fe@MSCs. Inset: A representative high-resolution TEM (HRTEM) image. c Protein bands analysis of MSCs, Cyp-PMAA-Fe, and Cyp-PMAA-Fe@MSCs. Samples were run on polyacrylamide gel electrophoresis at equivalent concentration and stained with Coomassie Brilliant Blue. d T1-weighted MR images of Cyp-PMAA-Fe@MSCs solutions at different PMAA concentrations. e T1 relaxation rate (r1) of Cyp-PMAA-Fe@MSCs solutions measured at different PMAA concentrations. f Ultraviolet–visible-NIR absorbance spectra of cypate dispersed in methanol, as well as PMAA-Fe and Cyp-PMAA-Fe@MSCs dispersed in DI water. (g, h) Dynamic Light Scattering distribution of Cyp-PMAA-Fe (G) and Cyp-PMAA-Fe@MSCs (h) in PBS. (i) Photothermal heating curves of Cyp-PMAA-Fe@MSCs as well as DI water and PMAA-Fe@MSCs irradiated under 808 nm laser for 5 min with different laser power densities