Fig. 7
In vivo synergistic phototherapy of TPP-PPG@ICG on MG63/Dox tumor xenografts. a NIR FL imaging of MG63/Dox tumor xenografts exposed to 808-nm laser irradiation (0.6 W/cm2, 5 min), 0.5, 1, 4, 8, 12 and 24 h after tail vein injection of TPP-PPG@ICG, and c the dissected organs from the MG63/Dox tumor-bearing mice: the tumor, the lungs, the liver, the spleen, the kidneys, the heart and the muscle). b IR thermal imaging of MG63/Dox tumor xenografts exposed to 808-nm laser irradiation (0.6 W/cm2, 5 min), 24 h after tail vein injection with PBS and TPP-PPG@ICG. d Photographs of representative tumors resected from different groups on days 0, 7, and 14, as indicated. e Tumor volumes of MG63/Dox tumor xenografts, f body weights of different groups of mice, and g H&E and h TUNEL staining of tumor sections of different groups. TUNEL-staining images for the control, TPP-PPG@ICG + no laser, and TPP-PPG + laser groups are shown in Additional file 1: Fig. S9)