Central composite design for the development of carvedilol-loaded transdermal ethosomal hydrogel for extended and enhanced anti-hypertensive effect

Table 1 Solubility studies of carvedilol in different media (Mean ± S.D, n = 3)

S. no	Medium composition (Ethanol: D/W) % (v/v)	Solubility (mg/ml)
1	20:80	0.22 ± 0.01
2	30:70	0.34 ± 0.08
3	40:60	0.57 ± 0.06
4	50:50	0.76 ± 0.11

ISSN: 1477-3155