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Table 2 The upper and lower limits of the independent variables for CCD

From: Central composite design for the development of carvedilol-loaded transdermal ethosomal hydrogel for extended and enhanced anti-hypertensive effect

Independent variables

Levels

Low

Medium

High

X1 (Lipid) % (w/v)

2

3.5

5

X2 (Ethanol) % (v/v)

20

30

40

X3 (PG) % (v/v)

5

7.5

10

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Journal of Nanobiotechnology

ISSN: 1477-3155

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