Table 8 Physicochemical studies of carvedilol ethosomal gel formulations
Formulation Code | Viscosity (Pa.s) | pH value | Spreadability (g.cm/sec) | Drug content (%) |
|---|---|---|---|---|
G1 | 1.2 ± 0.2 | 5.44 | 7.80 ± 0.28 | 94.57 ± 0.54 |
G2 | 1.8 ± 1.0 | 5.68 | 8.24 ± 0.32 | 99.82 ± 0.62 |
G3 | 2.8 ± 1.5 | 5.81 | 6.57 ± 0.17 | 98.43 ± 0.23 |
G4 | 3.4 ± 0.52 | 5.54 | 6.20 ± 0.33 | 97.81 ± 0.13 |
G5 | 9.3 ± 1.0 | 5.93 | 6.82 ± 0.48 | 98.24 ± 0.44 |
G6 | 19.7 ± 1.5 | 5.84 | 5.37 ± 0.12 | 99.21 ± 0.46 |
G7 | 25.6 ± 5.7 | 5.61 | 7.90 ± 0.36 | 99.50 ± 0.25 |