TY - JOUR AU - Sadalage, Priyadarshani S. AU - Patil, Reshma V. AU - Havaldar, Darshana V. AU - Gavade, Shruti S. AU - Santos, Ana Cláudia AU - Pawar, Kiran D. PY - 2021 DA - 2021/03/25 TI - Optimally biosynthesized, PEGylated gold nanoparticles functionalized with quercetin and camptothecin enhance potential anti-inflammatory, anti-cancer and anti-angiogenic activities JO - Journal of Nanobiotechnology SP - 84 VL - 19 IS - 1 AB - The development of nano delivery systems is rapidly emerging area of nanotechnology applications where nanomaterials (NMs) are employed to deliver therapeutic agents to specific site in a controlled manner. To accomplish this, green synthesis of NMs is widely explored as an eco-friendly method for the development of smart drug delivery system. In the recent times, use of green synthesized NMs, especially metallic NMs have fascinated the scientific community as they are excellent carriers for drugs. This work demonstrates optimized green, biogenic synthesis of gold nanoparticles (AuNPs) for functionalization with quercetin (QT) and camptothecin (CPT) to enhance potential anti-inflammatory, anti-cancer and anti-angiogenic activities of these drugs. SN - 1477-3155 UR - https://doi.org/10.1186/s12951-021-00836-1 DO - 10.1186/s12951-021-00836-1 ID - Sadalage2021 ER -