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Table 2 The classification of functional MeSNs for cancer therapy

From: Engineering of bioactive metal sulfide nanomaterials for cancer therapy

Therapy strategies

Functional MeSNs

Cargoes

Release patent

Synergistic treatment

Ref.

Photothermal therapy

Chitosan-stabilized CuS NPs

NA

NA

NA

[19]

RGD and TAT peptides modified mesoporous silica coated CuS NPs

NA

NA

NA

[12]

Clearablemanganese-doped CuS nanodots

NA

NA

NA

[144]

Ni9S8 NPs

NA

NA

NA

[45]

Bi2S3-gold heterojunction nanorods

NA

NA

NA

[51]

Nanoceria decorated flower-like MoS2 nanoflakes

NA

NA

NA

[46]

Gold/gold Sulfide NPs

NA

NA

NA

[146]

ReS2 NPs

NA

NA

NA

[22]

BSA and PEG modified RuS1.7 nanoclusters

NA

NA

NA

[98]

Cyclic RGD modified Ag2S NPs

NA

NA

NA

[47]

Erythrocyte-cancer hybrid membrane camouflaged hollow CuS NPs

DOX

Photothermal sensitive

Chemotherapy

[39]

Doxorubicin and chlorin e6 loaded hollow CuS NPs

Dox and Chlorin e6

Photothermal sensitive

Chemotherapy

[85]

Mesoporous SiO2 encapsulated CuS NPs

siRNA and Adriamycin

Photothermal sensitive

Chemotherapy

[90]

Hollow mesoporous NiS NPs

DOX

pH sensitive

Chemotherapy

[48]

Antibody-functionalized Bi2S3@mesoporous silica core-shell NPs

DOX

pH and temperature sensitive

Chemotherapy

[89]

SnS nanosheets

DOX

NA

Chemotherapy

[72]

Polyethylene glycol TaS2 nanosheets

DOX

Photothermal and moderate acidic pH sensitive

Chemotherapy

[40]

Urchin-like Bi2S3 NPs

DOX

Photothermal sensitive

Chemotherapy

[69]

PEG modified iron oxide-hydroxide nanospindles

NA

pH sensitive Fe2+ release

PTT

[16]

WS2 nanosheets

Photosensitizer

NA

PDT

[41]

Photodynamic therapy

Co9S8 nanodots

NA

NA

PTT

[67]

Ag2S NPs

NA

NA

NA

[66]

Transferrin modified hollow mesoporous CuS NPs

Artesunate

pH sensitive

Chemotherapy

[70]

Bi2S3 nanorods

Zinc protoporphyrin

NA

NA

[50]

Radiotherapy

Melanin-PEG coated CuS NPs

DOX

pH sensitive

Chemotherapy

[13]

Bi2S3@BSA

MTX

Proteinase

Chemotherapy

[57]

Folic acid conjugated Bi2S3@BSA

Curcumin

Sustained release

Chemotherapy

[56]

Platelet membrane camouflaged mesoporous silica-coated Bi2S3 nanorods

NA

NA

PTT

[49]

Ultrasmall Bi2S3 NPs

NA

NA

PTT

[31]

Gold-gold sulfide nanoshells

NA

NA

NA

[55]

Lipoic acid-PEG modified WS2 quantum dots

NA

NA

PTT

[33]

Chemodynamic therapy

Layered double hydroxides-CuS nanocomposites

NA

Photothermal active Cu2+ release

PTT and PDT

[30]

PEG modified iron oxide-hydroxide nanospindles

NA

pH sensitive Fe2+ release

PTT

[16]

PVP-modified CuS nanocrystals

NA

Photothermal active Cu2+ release

PTT and PDT

[52]

Gas therapy

Ferrous sulfide embedded FeS@BSA nanoclusters

NA

pH sensitive H2S release

CDT

[14]

MnS NPs

NA

NA

CDT

[64]

PVP-modified multifunctional Fe1 − xS NPs

NA

pH sensitive H2S release

PTT and CDT

[140]

ZnS NPs-decorated silica fibre mesh

DOX

pH sensitive H2S release

Chemotherapy

[21]

Immunotherapy

Maleimide polyethylene glycol modified CuS NPs

Tumor antigens

Photothermal sensitive

PTT

[44]

Bi2S3 NPs

Ganoderma lucidum polysaccharide

NA

Radiotherapy

[15]