Fig. 6

SeNPs inhibit the epidermal thickness. H&E stained skin sections of different treatment groups were observed for evaluation of epidermal thickness in these groups. Topical application of SeNPs significantly inhibited acanthosis in IMQ-induced mice and these images were captured at a × 200 and b × 400 magnification. (C) Epidermal hyperplasia was measured and represented as bar graph. Data represents Mean ± SD (n = 5). ****p < 0.0001 is significantly different from the normal control group; ^p < 0.05, ^^p < 0.01, and ^^^p < 0.001 is significantly different from the IMQ group