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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Selenium nanoparticles produce a beneficial effect in psoriasis by reducing epidermal hyperproliferation and inflammation

Fig. 8

SeNPs inhibit the keratinocyte proliferation and epidermal hyperplasia. a–h Cells and i–p Mice were treated with SeNPs with various concentrations and protein was extracted to evaluate the protein expression. Ki67, Cyclin D1, PCNA, and mTOR proteins and phosphorylation of Akt, STAT3, and GSK3β was determined by Immunoblotting. Data represents Mean ± SD (in vitro n = 3; in vivo n = 5). *p < 0.05, ***p < 0.001, and ****p < 0.0001 are significantly different from the normal control group; ^^p < 0.01, ^^^p < 0.001, and ^^^^p < 0.0001 are significantly different from the EGF and IMQ groups

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