Fig. 4

Zeta potential changes of P. aeruginosa after incubation with SCSMs and SCUMs under pH 7.4 and 5.5 for different periods of time (0–24 h) (a). Qualitative (b) and quantitative (c) cellular uptake of P. aeruginosa incubated with Cy5.5-SCSMs and Cy5.5-SCUMs for different periods of time (0.5–24 h) under pH 7.4 and 5.5. BLI assay for the interaction between b-LPS and SCSMs under pH 7.4 (d) and 5.5 (e), respectively. pH-dependent penetration and bacterial targeting of Cy5.5 loaded micelles in P. aeruginosa biofilms at pH 7.4 and 5.5, respectively (f)