Skip to main content
Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Ruthenium-loaded mesoporous silica as tumor microenvironment-response nano-fenton reactors for precise cancer therapy

Fig. 10

Inhibition of ROS decreased Ru@SiO2-PA-induced anticancer activity. a Inhibition of ROS by glutathione (GSH) inhibited Ru@SiO2-PA-induced dysfunction of MAPKs and PI3K/AKT pathways and DNA damage. b Inhibition of ROS inhibited Ru@SiO2-PA-induced anticancer activity. SGC-7901 cells were pre-treated with 5 mM GSH for 2 h and co-treated with 5 μg/ml Ru@SiO2-PA for 72 h. Protein expression was examined by western blot analysis. Cells viability was assayed by MTT assay. Bars with different letters indicate the P < 0.05 level

Back to article page