Fig. 6
Ru@SiO2-PA inhibited SGC-7901 tumor growth in vivo. a Images of nude mice bearing SGC-7901 tumor xenografts. b Tumor images. c Real-time change curve of tumor volume. d Real-time change curve of body weight. SGC-7901 cells (107 cells) were subcutaneously injected into the nude mice. After 7-days growth, mice were given 2.5 and 5 mg/kg Ru@SiO2-PA every other day for 21 days. The nude mice bearing SGC-7901 tumor xenografts were imaged. The real-time change curve of tumor volume and mice body weight were measured. e Ru@SiO2-PA induced caspase-3 activation in vivo. Caspase-3 expression was detected by western blot analysis. All experiments were repeated at least 3 times. Bars with “**” represent P < 0.01 level