Fig. 7

Cell morphology, viability, and function of PDGF-BB- and rosuvastatin-treated SMCs. a Cell morphology of control, PDGF, PDGF + Rosu, and Rosu groups. Scale bar, 20 µm. b Cell proliferation rate of control, PDGF, PDGF + Rosu, and Rosu groups. Scale bar, 100 µm. Bar graph showing the cell proliferation rate (%). Data represent the mean ± SD (n = 3/group). ****p < 0.0001. c Wound-healing assays and corresponding representative images of SMC migration in control, PDGF, PDGF + Rosu, and Rosu groups according to scratch assay. Scale bar, 100 µm. Data represent the mean ± SD (n = 3/group). *p < 0.05, **p < 0.01, ***p < 0.001. d Transwell assays and corresponding representative images of crystal violet-stained invasive cells in the lower chamber. Scale bar, 100 µm. Data represent the mean ± SD (n = 3/group). *p < 0.05, **p < 0.01