Fig. 7

a Thermal images of MDA-MB-231-tumor-bearing mice from different treating groups (PBS + laser, Lipo/ICG + laser, and Lipo/pB-DOX/ICG + laser) under 808 nm laser irradiation for different irradiation periods. b Temperature change curves at the tumor sites of different treatment groups during 808 nm laser irradiation. c Tumor volume curves of different groups after various treatments including: PBS, PBS + laser, DOX·HCl, Lipo/pB-DOX, Lipo/ICG + laser, Lipo/pB-DOX/ICG, and Lipo/pB-DOX/ICG + laser. d Photographs of tumor tissues removed from groups treated with different formulations after 21 d. The red circles indicated disappeared tumors. e Tumor weights of each group at the end of experiment and IRT. f Body weight curves of MDA-MB-231 tumor-bearing mice for each group. g Representative histological images of tumor and heart samples from the treated mice. (The data are shown as mean ± SD, n = 5 per group, NS, no significance, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)