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Table 2 Perfusion kinetics of carbon particles in fetal and maternal perfusates determined by femtosecond pulsed laser illumination

From: Label-free detection of uptake, accumulation, and translocation of diesel exhaust particles in ex vivo perfused human placenta

Carbon particle load (SD)

Perfusion time ( min)

Fetal perfusates (no. particles/mL)

p-valuea

Maternal perfusates (no. particles/mL)

p-valueb

Exposed (N = 4)

0

7.7 × 105 (8.8 × 105)

/

1.7 × 108 (3.6 × 107)

/

60

12 × 105 (8.7 × 105)

0.7258

1.1 × 108 (2.5 × 107)

< 0.0001*

180

8.1 × 105 (13 × 105)

0.9997

1.1 × 108 (2.4 × 107)

< 0.0001*

360

3.7 × 105 (6.2 × 105)

0.7258

1.0 × 108 (1.7 × 107)

< 0.0001*

Control (N = 2)

0

0.0

/

2.2 × 105 (5.4 × 105)

/

60

1.5 × 105 (2.3 × 105)

0.6930

0.7 × 105 (1.8 × 105)

0.9203

180

1.5 × 105 (2.3 × 105)

0.6930

3.7 × 105 (4.3 × 105)

0.9203

360

3.7 × 105 (3.3 × 105)

0.0550

2.2 × 105 (3.7 × 105)

> 0.9999

  1. ANOVA analysis of variance, SD standard deviation
  2. *p < 0.05 was considered statistically significant as analyzed by one-way ANOVA with Tukey’s multiple comparison correction
  3. aDifferences in carbon particle concentration determined in fetal perfusates over time compared to the initial amount
  4. bDifferences in carbon particle concentration determined in maternal perfusates over time compared to the initial amount. Data represent the mean DEP load (SD) in fetal and maternal perfusates collected after different perfusion times of 4 (exposed), and 2 (control) independently perfused placentae