Fig. 4

PGZ-exos enhanced the angiogenic ability of HUVECs inhibited by HG. B A transwell assay was used to assess the cell migration of HUVECs. Scale bar: 50 µm. B A tube formation assay was performed to visualize the cell capillary network formation of HUVECs. Scale bar: 100 µm. C In vitro wound healing assay of the HUVECs. Scale bar: 200 µm. D Quantitative analysis of the number of migrating cells in the four groups. E Quantitative analysis of tube formation in the four groups. F Quantitative analysis of the rate of wound closure in the four groups. Data are presented as means ± SD from three independent experiments. *P < 0.05 versus the control (con) group