Fig. 7

LY294002 inhibited the PGZ-Exos-induced activation of the PI3K/AKT/eNOS pathway in HUVECs. A Western blotting showing the protein expression of AKT, p-AKT, PI3K and p-PI3K of the HUVECs treated with HG medium supplemented with PGZ-Exos and PGZ-Exos + LY 294002. B Quantitative analysis of the protein level of p-AKT/AKT in the four groups. C Quantitative analysis of the protein level of p-PI3K/PI3K in the four groups. D Western blotting showing the protein expression of eNOS, p-eNOS and PTEN. E Quantitative analysis of the protein level of p-eNOS/eNOS in the four groups. F Quantitative analysis of the protein level of PTEN in the four groups. Data are presented as means ± SD from three independent experiments. *P < 0.05 versus the control (con) group