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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Tubule-specific protein nanocages potentiate targeted renal fibrosis therapy

Fig. 4

K3-HBc/CLT is specifically targeting renal tubular epithelial cells of UUO mice. A, B Ex vivo fluorescence images of major organs harvested from UUO mice at 1 h post injection of Cy5.5-labeled K3-HBc/CLT or HBc-183/CLT NCs on the first and 7th day. C, D Fluorescence intensity from excised kidneys (n = 3). E Immunohistochemical staining of kidney sections at 4 h after injected with FITC-labeled HBc-183/CLT or K3-HBc/CLT NCs. Scaler bar, 500 μm (upper right panel), 20 μm (left panel) (***p < 0.001)

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