Fig. 2

Effects of CrCi-CDs on neurological deficit scores, infarct volume. A Representative TTC staining of brain slices in rats, 24 h after MCAO. Neurologic deficit scores are presented as the median (range), were evaluated at 24 h after MCAO. *p < 0.05, **p < 0.01 versus vehicle group, n = 18. B Statistical analysis of the percentage of infarct volume was determined, 24 h after MCAO. C Effects of CrCi-CDs on neurological deficit scores. D Brain photos and brain slices with HE stains. E The ultra-structure of neuron in cortex, EM × 5 k, 20 kA. F Permeability of BBB as revealed by evans blue staining. G Effects of CrCi-CDs on mNSS score. Bar graph shows the levels of IL-6 (H), and TNF-α (I) in the cortex of the ischemic hemisphere 24 h after reperfusion