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Table 1 All the reports on the aptamers of heavy metal ions since the 21th century

From: Advances in aptamer screening and aptasensors’ detection of heavy metal ions

Target Name Method Cycle Kd Sequence Refs
As3+ Ars-3 Affinity Chromatography 10 7.05 ± 0.91 nM TTACA GAACA ACCAA CGTCG CTCCG GGTAC TTCTT CATCG [54]
As3+ Ars-7 Affinity Chromatography 10 13.0 ± 1.25 nM ATGCA AACCC TTAAG AAAGT GGTCG TCCAA AAAAC CATTG [54]
Cd2+ Cd-4 Affinity Chromatography 11 34.5 nM GGACT GTTGT GGTAT TATTT TTGGT TGTGC [53]
Cd2+ CD-2–2 Affinity Chromatography 14 / CTCAG GACGA CGGGT TCACA GTCCG TTGTC [51]
Pb2+ Pb-14 s Affinity Chromatography 18 0.76 ± 0.18 μM GACGA CGGCC AGTAG CTGAC ATCAG TGTAC GATCT AGTCG TC [52]
Pb2+ M4-16 molecular dynamics   / GGGA GGGT GGGT GGGA [73]
Zn2+ Zn-6m2 Affinity Chromatography 12 15 μM GCATC AGTTA GTCAT TACGC TTACG GCCCG ATCCT AACTT GCTAC TGTCC CCTTC CGCCA GTTGT GCCGC GATTG TGAAG TCGTG TCCC [50]
Co2+ NO.20 Affinity Chromatography 15 1.1 ± 0.15 mM GGGCA UACGU UAGGC UGUAG GCGAG GUGGA AGAAA CGCGG UAAUA GCCUC AGCGU AGCAU AUGCA AGCUU CG [55]
Pd2+ DNA 01 GO 13 4.6 ± 1.17 μM GGGCG GACGC TAGGT GGTGA TGCTG TGCTA CACGT GTTGT [58]
Hg2+ SSA-Hg II SS-PD 4 2.27 ± 0.76 μM TCCAA GCTCT TTTCT GCAGC TATTC TTGTT TCGAA ACTTG CTAAG CTGCG T [71]
Cu2+ SSA-Cu II SS-PD 4 47.15 ± 22.16 μM ATCGC GATAT TTTCT GTAGC GATTC TTGTT TGAGC GCTCG GTACG AACAG A