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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Bone mesenchymal stem cells stimulation by magnetic nanoparticles and a static magnetic field: release of exosomal miR-1260a improves osteogenesis and angiogenesis

Fig. 4

Magnetic stimulation enhances the angiogenic effect of exosomes in HUVECs. (*) p < 0.05, (**) p < 0.01, (***) p < 0.001. a, b Assessment of the migratory activity of HUVECs at 24 h by scratch wound assay and quantitative analysis of the wound recovery rate; the yellow dashed lines are the edges of the cell migration. c, d Transwell assay and quantitative analysis of the cell migration rate. e, f Tube formation by HUVECs and quantitative analysis of the average tube length. g mRNA expression levels of VEGF, ANG-1 and HIF-1α. h Western blotting assay of the protein expression of VEGF, ANG-1 and HIF-1α

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