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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Pregnancy exposure of titanium dioxide nanoparticles causes intestinal dysbiosis and neurobehavioral impairments that are not significant postnatally but emerge in adulthood of offspring

Fig. 5

Pregnancy exposure to TiO2NPs did not cause the delays in developmental milestones and the perturbations in neurobehavioral development of offspring. The potential effects of TiO2NPs on the developmental milestones were assessed each day until each milestone attained. A Effects of TiO2NPs on the day of fur development, incisor eruption, eye opening, testes descent and vaginal opening in offspring. B Effects of TiO2NPs on the grasping time in the forelimb grip strength test at postnatal day (PD) 12. C Effects of TiO2NPs on the latency of cliff avoidance at PD12. D Effects of TiO2NPs on the latency of negative geotaxis at PD14 and PD18. E Effects of TiO2NPs on the latency of surface right reflex at PD14 and PD18. Data were presented as mean ± S.E.M. Statistical analysis was performed by using repeated-measure ANOVA or independent student t test or Mann–Whitney U test

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Journal of Nanobiotechnology

ISSN: 1477-3155

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