Fig. 8From: Pregnancy exposure of titanium dioxide nanoparticles causes intestinal dysbiosis and neurobehavioral impairments that are not significant postnatally but emerge in adulthood of offspringPregnancy exposure to TiO2NPs resulted in anxiety-like behavior in offspring at PD49 but not presented at PD21. After pregnancy exposure to TiO2NPs, the anxiety-like behavior in offspring was evaluated by elevated plus maze at postnatal day (PD) 21 and PD49. A Effects of TiO2NPs on the duration in the open arms. B Effects of TiO2NPs on the distance in the open arms. C Effects of TiO2NPs on the frequency of entries into open arms. D The representative track maps in the elevated plus maze. E Effects of TiO2NPs on the head dips. Data were presented as mean ± S.E.M. Statistical analysis was performed by using repeated-measure ANOVA or independent student t test or Mann–Whitney U testBack to article page