Fig. 6
In vivo therapeutic effects for tumor in mice. A Representative fluorescence images using an in vivo imaging system (IVIS) depicting in vivo nanoparticles after intratumoral injection in different samples. HeLa cells were subcutaneously inoculated in mice and allowed to grow to 50 mm3 before being treated with the nanosystem. B The survival analysis of established HeLa xenografts in mice after treatment ((DOC + E6E7) @DOTAP), control (DOC@DOTAP, E6E7@DOTAP), or untreated (PBS only) in days. C Tumor volume was monitored for 31 days. D and E Size and weight of HeLa xenografts tumors for treating with different samples. *p < 0.05, **p < 0.01 vs. control. #p < 0.05, ##p < 0.01, ###p < 0.05