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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: WRAP-based nanoparticles for siRNA delivery: a SAR study and a comparison with lipid-based transfection reagents

Fig. 6

Comparison of the lead WRAP-based PBNs with other transfection reagents. A Relative Luc activity (%) after WRAP:siLuc PBN transfection on U87 cells compared to other lipid-based transfection reagents (siRNA = 50 nM). B Clonogenic assay after WRAP:siLuc PBNs transfection on U87 cells compared to other lipid-based transfection reagents (siRNA = 50 nM). Dashed lines represent the range of 100 ± 20% showing no impact on the cell viability. Abbreviations: siLuc = firefly luciferase siRNA, N.T. = non-treated cells, Ctrl = Controls. Data represent mean ± SD, with n = 2 independent experiments in triplicate for luciferase assay and n = 4 independent experiments in duplicate for clonogenic assay

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