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Table 2 Protection efficiency of the immunized SPF chickens after challenged with the highly virulent NDV strain F48E9

From: Intranasal immunization with O-2′-Hydroxypropyl trimethyl ammonium chloride chitosan nanoparticles loaded with Newcastle disease virus DNA vaccine enhances mucosal immune response in chickens

Groups

Number of dead chickens/total number of chickens

Mortality (%)

Protection (%)

O-2'-HACC/pFDNA i.n

0/7

0

100

O-2'-HACC/pFDNA i.m

0/7

0

100

Live attenuated NDV vaccine i.m

0/7

0

100

pVAX I -F(o)-C3d6 i.m

2/7

28.6

71.4

O-2′-HACC i.m

7/7

100

0

PBS i.m

7/7

100

0