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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Imaging asparaginyl endopeptidase (AEP) in the live brain as a biomarker for Alzheimer’s disease

Fig. 3

Cellular uptake of AuNPs-Cy5.5-A&C and its fluorescence intensity in different cell lines. A Uptake of AuNPs-Cy5.5-A&C into cytoplasm after incubation with C6 cells for 24 h. Immunofluorescence images of AEP was co-localized with AuNPs-Cy5.5-A&C in cytoplasm. B AuNPs-Cy5.5-A&C was co-localized with LysoTracker Green DND-26 in C6 cells. C Enzymatic activity of AEP in C6 cells is higher than other cell lines. *P < 0.05, one-way ANOVA. n = 3 independent experiments. D Fluorescent intensity of AuNPs-Cy5.5-A&C in C6 cells is significantly higher than other cell lines. *P < 0.05, one-way ANOVA. n = 3 independent experiments, and 60–70 cells were imaged per experiment

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