Fig. 8

Imaging of AuNPs-Cy5.5-A&C in brains of the APP/PS1 and age-matched WT mice. A–C Two group of mice at 5, 6, and 8 months of age, imaging of the brain was performed at 0.5, 2, 4 and 6 h post intracerebroventricular injection of AuNPs-Cy5.5-A&C. D–F Ratio: the fluorescence intensity (FI) at 6 h divided by FI at 0.5 h post injection. *P < 0.05, comparison between APP/PS1 and age-mated WT mice, Student’s t-test. n = 5 mice per group