Fig. 10

In vivo anti-metastasis effect. a Digital photographs of excised lung tissues at the end of the experiment (day 21 after tumor inoculation). Mice were injected with 4T1 cells through tail vein and administrated of PBS, free CDDP, TD, TD/CDDP, TP/CDDP or CTP/CDDP on days 2, 4, 6 and 8 after tumor inoculation. b Quantitative analysis of the metastatic lung nodules. c H&E staining of excised lung tissues. Data are expressed as mean ± SD (n = 5), ***p < 0.001