Skip to main content
Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Nitric oxide-releasing micelles with intelligent targeting for enhanced anti-tumor effect of cisplatin in hypoxia

Fig. 5

Mechanism of reversing drug resistance in vitro. a CDDP retention after incubation with free CDDP, TD/CDDP, TP/CDDP and CTP/CDDP for 20 h in hypoxic 4T1 cells. b Intracellular GSH levels of hypoxic 4T1 cells treated with various drug formulations for 24 h. c Western blot of indicated proteins expression in hypoxic 4T1 cells after 24 h incubation with different drugs. d The expression of relative proteins was calculated by the signal intensity of protein bands. Cells treated with PBS were used as control. Data are expressed as mean ± SD (n = 3), **p < 0.01, ***p < 0.001

Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us