Fig. 6

Synergetic anti-metastasis effect in vitro. a Images of 4T1 cells treated with PBS, free CDDP, TD, TD/CDDP, TP/CDDP and CTP/CDDP in wound healing assay at 0 and 24 h. b The quantification of wound healing assay was calculated as: percent closure (%) = length of cell migration/width of wounds × 100. Percent closure of control group was standardized as 100%. c Migration and invasion activities of 4T1 cells treated with various drug formulations for 24 h. The quantification of d migration and e invasion activities. Cells treated with PBS were used as control. Data are expressed as mean ± SD (n = 3), **p < 0.01