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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: A nitroxides-based macromolecular MRI contrast agent with an extraordinary longitudinal relaxivity for tumor imaging via clinical T1WI SE sequence

Fig. 7

a Viabilities of 4T1 cells and HUVEC cells after incubation with Linear pDHPMA-mPEG-Ppa-PROXYL at various concentrations for 24 h. b Erythrocyte aggregates and morphologies in PBS or Linear pDHPMA-mPEG-Ppa-PROXYL solutions at 1, 2, and 5 mg/mL. c Red blood cell hemolysis induced by Linear pDHPMA-mPEG-Ppa-PROXYL. d Hemolysis rates induced by Linear pDHPMA-mPEG-Ppa-PROXYL at different concentrations. e Blood chemistry indexes in mice injected with saline, Linear pDHPMA-mPEG-Ppa-PROXYL and 3-CP for 24 h. f Histological images of mice 1 day after injection of saline (Group 1), 3-CP (Group 2) and Linear pDHPMA-mPEG-Ppa-PROXYL (Group 3). Scale bar: 10 μm

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