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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: An in situ tissue engineering scaffold with growth factors combining angiogenesis and osteoimmunomodulatory functions for advanced periodontal bone regeneration

Fig. 6

Evaluation of the bone remodeling at week 1 and 2. a Micro-CT reconstructed 3D images of the rat mandibular bone defects. Green color displayed the newly formed bone in the defect sites. b–d Quantification of BS/TV (b), Tb. Th (c) and Tb. Sp (d). e Representative H&E staining images of the mandible sections. The visual fields framed by the black line were magnified in the figures below. f The percentage of new bone formation at two time points. g Representative TRAP staining images of mandibular bone defects. Yellow arrows indicated osteoclasts in the trabecular bone surface. h The number of TRAP+ cells in defect regions. *P < 0.05, **P < 0.01, ***P < 0.001

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