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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury

Fig. 7

CD73+hucMSC-EVs regulate the production of proinflammatory cytokines after SCI. A Cytokines of spinal samples from SCI mice are quantitative analyzed by Bio-Plex system 3d after SCI and hucMSC-EVs/CD73+hucMSC-EVs treatment. BH The protein levels analyzed by Bio-Plex system, such as IL-1β, IL-6, TNF-α, IFN-γ, MCP-1 and MIP-1β are significantly decreased, while IL-4 and IL-10 are significantly increased. IL The protein levels, including IL-1β, IL-6, TNF-α, and IL-10, are also analyzed by ELISA. (*p < 0.05 versus SCI group, #p < 0.05 versus SCI+CD73+hucMSC-EVs group, n = 5)

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