Table 3 Applications of MI in biomedical fields
MI with improved material functions | Polymers | Template | Applications |
|---|---|---|---|
Insulin- imprinted polymer | Mixture of methacrylic acid and N-hydroxyethyl acrylamide | Insulin | Reducing insulin release especially when taking insulin orally [55] |
DOX-imprinted polymer | Mesoporous silica nanoparticles | DOX | Improvement in efficacy and release of the drug [63] |
L-DOPA-imprinted polymer | β-Cyclodextrin and 1,1′-carbonyldiimidazole | L-DOPA | Enhanced prolonged release of the drug with an excellent clearance profile [67] |
DFCR-imprinted polymer | Boronic acid | DFCR | Helps in the control released of the drug and increased selectivity to the target site [71] |
5-Fluorouracil- imprinted polymer | Magnetic fluorescent core | 5-fluorouracil | Increased efficacy of the drug 25 times than the drug alone [77] |
Sunitinib-imprinting polymer | Fluorescent MIP | Sunitinib | Monitoring the drug fluorescently [75] |
B family vitamin-imprinting polymers | Hydrophilic multi-template MI biopolymers (mt-MIBP) using chitosan as a bio-substance | Riboflavin, nicotinamide, and pyridoxine | Separation and determination of these vitamins in orange juice [78] |
Bovine hemoglobin- imprinting with a fluorescence sensor | Tricolor-emission sensor that was constructed with a mixture of blue, green, and red- emission MIPs | Bovine hemoglobin | Detection and visualize of bovine hemoglobin [79] |