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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Improving anti-cancer drug delivery performance of magnetic mesoporous silica nanocarriers for more efficient colorectal cancer therapy

Fig. 8

Representative ex vivo fluorescence and magnetic resonance imaging (MRI). Fluorescence images taken for main organs (liver, kidney, spleen, heart, and lung) and tumor at A 12 and B 24 h after injection of free DOX, PEG-Au-NPs@DOX and Apt-PEG-Au-NPs@DOX (DOX final concentration was 1 mg/kg). The T2-weighted coronal and axial images of the HT-29 tumor bearing C57BL/6 mice 12 h post injection of C PBS, D PEG-Au-NPs@DOX and E Apt-PEG-Au-NPs@DOX. The areas of the tumor are marked with a circle. SPION Superparamagnetic iron oxide nanoparticle, MSN Mesoporous silica nanoparticle, PEG Polyethylene glycol, NP nanoparticle, Apt Aptamer, DOX Doxorubicin

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