Improving anti-cancer drug delivery performance of magnetic mesoporous silica nanocarriers for more efficient colorectal cancer therapy

Table 1 Characterization parameters of the prepared nanocarriers

Samples	Zeta potential (mV)	Particle size (nm)	BET surface area (m²/g)	Pore volume (cm³/g)	BJH pore diameter (nm)
SPION@MSNs	− 19.52 ± 1.85	24.37 ± 0.21	432.79	1.23	1.21
SPION@MSNs-NH₂	+ 15.35 ± 3.23	27.44 ± 1.83	ND	ND	ND
NPs@DOX	− 10.55 ± 1.00	32.38 ± 3.33	ND	ND	ND
Au-NPs@DOX	− 15.66 ± 0.82	39.71 ± 5.45	117.93	0.4	1.21
PEG-Au-NPs@DOX	− 18.50 ± 1.22	50.28 ± 4.76	ND	ND	ND
Apt-PEG-Au-NPs@DOX	− 19.79 ± 2.18	58.22 ± 8.54	ND	ND	ND

Particle size was measured by dynamic light scattering (DLS). Data are expressed as mean ± SD
BET Brunauer–emmett–Teller, BJH Barrett–Joyner–halenda, SPION Superparamagnetic iron oxide nanoparticle, MSN Mesoporous silica nanoparticle, DOX Doxorubicin, PEG Polyethylene glycol, Apt Aptamer, ND not determined

ISSN: 1477-3155