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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Simvastatin induced ferroptosis for triple-negative breast cancer therapy

Fig. 2

Schematic illustration of Fe3O4@PCBMA-SIM nanoparticles killing cancer cells (A); The degradation property of Fe3O4@PCBMA nanoparticles dispersed in different concentrations of GSH (0 mM and 10 mM) and pH values (5.0, 6.5 and 7.4) (B); Cumulative SIM releasing from Fe3O4-SIM and Fe3O4@PCBMA-SIM nanoparticles dispersed in 10 mM GSH (C); Cell viability of the MCF-7 (D) and MDA-MB-231 (E) cells after 48 h incubation with Fe3O4, Fe3O4@PCBMA, SIM, Fe3O4-SIM and Fe3O4@PCBMA-SIM suspensions; CLSM of control, Fe3O4@PCBMA, free SIM, Fe3O4-SIM and Fe3O4@PCBMA-SIM nanoparticles after uptake by MCF-7 and MDA-MB-231 cells (F)

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