Fig. 4
From: Simvastatin induced ferroptosis for triple-negative breast cancer therapy
Schematic illustration of ferroptosis mechanism (A); The GPX4 and HMGCR protein expression of MCF-7 cells after treated with Fe3O4@PCBMA, SIM, Fe3O4-SIM and Fe3O4@PCBMA-SIM (B, D, E); The GPX4 and HMGCR protein expression of MDA-MB-231 cells after treatment with Fe3O4@PCBMA, SIM, Fe3O4-SIM and Fe3O4@PCBMA-SIM (C, F, G); The HMGCR protein expression of MCF-7 cells and MDA-MB-231 cells and the corresponding intensity (H); Flow cytometry analysis of lipid hydroperoxides (LPO) generation in MCF-7 (I) and MDA-MB-231 cells (J)