Fig. 8From: A polydopamine nanomedicine used in photothermal therapy for liver cancer knocks down the anti-cancer target NEDD8-E3 ligase ROC1 (RBX1)In vitro anticancer activity of the genetic nanomedicine combined with photothermal therapy in Huh7 liver cancer cells. a Viability of the Huh7 cells after incubation with siNT or siRNA-loaded PDA nanomedicine (containing 2 μg/ml siRNA or siNT) in the absence or presence of laser irradiation for 48 h. b Flow cytometric analysis of Huh7 cell apoptosis on the basis of Annexin V and FITC-PI staining. c Statistical analysis of the apoptotic cells corresponding to b. Error bars represent the mean ± SD (standard deviation, n = 3), *p < 0.05, **p < 0.01, ***p < 0.001Back to article page