Skip to main content

Table 1 The survival and body weight changes of mice in the acute toxicity test

From: A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer

Groups

Amount (start/end)

Bodyweight (g)

Average weight change rate (%)

Start

End

Saline

5/5

18.36 ± 1.83

19.64 ± 1.60

6.97

FA-PEG-CM-β-CD

5/5

18.60 ± 0.51

19.28 ± 1.46

3.66

5-ASA

5/5

18.58 ± 0.41

19.44 ± 0.45

4.63

NaB

5/5

18.24 ± 0.53

19.14 ± 0.52

4.93

BBA

5/5

18.48 ± 0.63

18.16 ± 0.63

1.00

5-FU

5/5

18.82 ± 0.61

17.98 ± 0.80**

− 4.46*

BBA/CM-β-CD

5/5

18.57 ± 0.71

19.05 ± 1.59

2.56

BBA/FA-PEG-CM-β-CD

5/5

18.66 ± 0.59

19.74 ± 1.26

5.79

  1. Results were presented as mean ± SD (n = 5). Symbols represented statistical significance compared with saline group. P < 0.05, **P < 0.01