Fig. 5

In vivo investigation of the clusters. a Wound healing processes over time of TBI mice with and without treatment of clusters, and b showed wound remaining percentage over time. The Au₂₄Cu₁ and Au₂₄Cd₁ showed favorable therapeutic effect against TBI. c–f Indicators for oxidative stress, including SOD, GSH/GSSG, MDA, and H₂O₂, of TBI mice with or without treatment of clusters on days 7 and 14 post intervention (n = 3 per group). The clusters can rescue the level of SOD and GSH/GSSG decreased by TBI, and decrease the MDA and H₂O₂, indicative of alleviating the oxidative stress in vivo. Data are presented as mean ± SEM and compared with the Con groups, analyzed by one-way ANOVA with Tukey test (adjusted p values are shown, *p< 0.05, **p< 0.005)